Wei Shina
Personal profile:
Wei Shina: Female, Hebei Hengshui, Ph.D., associate researcher. Research interests: marine fish molecular immunology and functional genomics. He has presided over 3 national, provincial and ministerial projects, including 1 National Natural Science Foundation, 1 Natural Science Foundation of Guangdong Province, and 1 Open Project of Key Laboratory of Aquatic Economic Animal Pathogenic Biology and Epidemiology of Guangdong Province; One project of the Ministry of Oceans 863 and one international (regional) cooperation and exchange project of the National Natural Science Foundation of China. In recent years, 32 SCI papers have been published, including 4 SCI papers by the first author, 6 co-authors, and 22 SCI papers; the first author published 2 Chinese core journals; and participated in 6 patent applications.
Education experience:
2010.09-2013.07 Nanhai Institute of Oceanology, Chinese Academy of Sciences Department of Marine Biology 2007.09-2010.07
Guangdong Ocean University Master of Aquaculture Master
2002.09-2006.07 Hebei Normal University of Science and Technology Aquaculture Education Bachelor
Research projects:
1. The role and mechanism of the National Natural Science Foundation of China (41506176) grouper cysteine protease inhibitor B (Cystatin B) in iridovirus SGIV infection, 2016.01-2018.12, under research, presided over.
2. Research on the mechanism of action of the grouper's Cystatin C gene in iridovirus SGIV infection in Guangdong Province Natural Science Foundation PhD Foundation (2014A030310387), 2015.01-2018.01, under research, hosted.
3. Open project of the Key Laboratory of Pathogenic Biology and Epidemiology of Aquatic Economic Animals in Guangdong Province (GDOUKL1503) Study on the cloning, function and signaling pathway of the novel pattern recognition receptor NLR in the grouper, 2015.07-2017.07, in research, Hosted.
4. International (regional) cooperation and exchange project (31461163007) Research and development of new vaccines for fish iridescent virus, 2015.01-2017.12, in progress, participation.
5, the national 863 plan (2012AA092201-2) oblique grouper immunization / disease resistance related functional gene research, 2012.01-2014.12, has been completed, participated.
Published papers:
1. Wei S, Huang Y, Huang X, Qin Q*. Characterization of c-Jun from orange-spotted grouper, Epinephelus coioides involved in SGIV infection. Fish Shellfish Immunol. 2015; 43(1): 230-40. (第一作者)
2. Wei S, Huang Y, Huang X, Cai J, Wei J, Li P, Ouyang Z, Qin Q*. Molecular cloning and characterization of a new G-type lysozyme gene (Ec-lysG) in orange-spotted grouper, Epinephelus coioides. Dev Comp Immunol. 2014; 46(2): 401-12. (第一作者)
3. Wei S, Huang Y, Huang X, Cai J, Yan Y, Guo C, Qin Q*. Characterization of cathepsin B gene from orange-spotted grouper, Epinephelus coioides involved in SGIV infection. Fish Shellfish Immunol. 2014; 36(1): 194-205. (第一作者)
4. Wei S, Huang Y, Cai J, Huang X, Fu J, Qin Q*. Molecular cloning and characterization of c-type lysozyme gene in orange-spotted grouper, Epinephelus coioides. Fish Shellfish Immunol. 2012; 33(2) : 186-96. (First author)
5. Wei Shina, Jian Jichang*, Wu Zaohe, Lu Yishan, Yan Xiuying. Research progress in fish non-specific cytotoxic cells (NCC). China Fisheries Science. 2010; 17(2 ):
374-380 . (First author) 6. Wei Shina, Wang Wei, Lu Yishan, Wu Zaohe, Jian Jichang*. Optimization and purification of prokaryotic expression conditions of NCCRP-1 gene of red snapper. Journal of Guangdong Ocean University. 2010 30(6): 25-30. (first author)
7. Li P, Zhou L, Yu Y, Yang M, Ni S, Wei S*, Qin Q*. Characterization of DNA aptamers generated against the soft-shelled Turtle iridovirus with antiviral effects. BMC Vet Res. 2015; 11: 245. (Common author)
8. Li P, Yang M, Ni S, Zhou L, Wang Z, Wei S*, Qin Q*. Complete mitochondrial genome sequence of the pelagic chaetognath, Sagitta pacifica. Mitochondrial DNA. 2015; 18:1-2. (共同通讯作者)
9. Li P, Zhou L, Ni S, Xu M, Yu Y, Cai J, Wei S*, Qin Q*. Establishment and characterization of a novel cell line from the brain of golden pompano (Trachinotus ovatus). In Vitro Cell Dev Biol Anim. 2016; 52(4):410-8. (共同通讯作者)
10. Li P, Zhou L, Wei J, Yu Y, Yang M, Wei S*, Qin Q*. Development and characterization of aptamer-based enzyme-linked apta-sorbent assay for the detection of Singapore grouper iridovirus infection. J Appl Microbiol. 2016; 121(3): 634-43. (共同通讯作者)
11. Zhou L, Li P, Yang M, Yu Y, Huang Y, Wei J, Wei S*, Qin Q*. Generation and characterization of novel DNA aptamers against coat protein of grouper nervous necrosis virus (GNNV) with antiviral activities and delivery potential in grouper cells. Antiviral Res. 2016; 129:104-14. (共同通讯作者)
12. Yu Y, Wei S, Wang Z, Huang X, Huang Y, Cai J, Li C, Qin Q*. Establishment of a new cell line from the snout tissue of golden pompano Trachinotus ovatus, and its application in virus susceptibility. J Fish Biol. 2016; 88(6):2251-62.
13. Li P, Wei S, Zhou L, Yang M, Yu Y, Wei J, Jiang G, Qin Q*. Selection and characterization of novel DNA aptamers specifically recognized by Singapore grouper iridovirus-infected fish cells. J Gen Virol. 2015; 96(11): 3348-59.
14. Cai J, Wei S, Wang B, Huang Y, Tang J, Lu Y, Wu Z, Jian J*. Cloning and expression analysis of nonspecific cytotoxic cell receptor 1 (Ls-NCCRP1) from red snapper (Lutjanus sanguineus). Mar Genomics. 2013; 11: 39-44.
15. Guo C, Huang Y, Wei S, Ou-yang Z, Yan Y, Huang X and Qin Q*. Establishment of a new cell line from the heart of giant grouper, Epinephelus lanceolatus (Bloch), and its application in toxicology and virus susceptibility. J Fish Dis. 2015; 38(2): 175-86.
16. Ji H, Wei J, Wei S, Yan Y, Huang Y, Huang X, Zhou S, Zhou Y, Qin Q*. Molecular cloning and expression of a C-type lectin-like protein from orange-spotted grouper Epinephelus coioides. J Fish Biol. 2014; 84(2): 436-47.
17. Li P, Yan Y, Wei S, Wei J, Gao R, Huang X, Huang Y, Jiang G, Qin Q*. Isolation and characterization of a new class of DNA aptamers specific binding to Singapore grouper iridovirus (SGIV) with antiviral activities. Virus Res. 2014; 188: 146-54.
18. Cai J, Huang Y, Wei S, Ouyang Z, Huang X, Qin Q*. Characterization of LPS-induced TNFα factor (LITAF) from orange-spotted grouper, Epinephelus coioides. Fish Shellfish Immunol. 2013; 35(6): 1858-66.
19. Cai J, Huang Y, Wei S, Huang X, Ye F, Fu J, Qin Q*. Characterization of p38 MAPKs from orange-spotted grouper, Epinephelus coioides involved in SGIV infection. Fish Shellfish Immunol. 2011; 31(6): 1129-36.
20. Huang X, Huang Y, Yang Y, Wei S, Qin Q*. Involvement of fish signal transducer and activator of transcription 3 (STAT3) in SGIV replication and virus induced paraptosis. Fish Shellfish Immunol. 2014; 41(2): 308-16.