Zhou Sheng

Profile:

Doctor, associate researcher, master's supervisor, agricultural science and Technology Commissioner of Guangdong Province, agricultural science and Technology Commissioner of Guangzhou City, scientist member of national marine fish industry system virus disease prevention and control post. The main research direction is the prevention and control of virus diseases and healthy cultivation technology of grouper, California perch and other fish; the isolation, screening and identification of probiotics in fish intestine; the influence and mechanism of probiotics and virus bacteria interaction on the health of cultured fish; the development of probiotic fermentation feed and biological products with disease resistance function. He has presided over 7 projects including National Natural Science Foundation of China, Guangdong Natural Science Foundation, China Postdoctoral fund, innovation and entrepreneurship fund of South China Agricultural University, participated in 10 national and provincial level projects, published 20 papers, participated in the compilation of 1 monograph, applied for 11 national invention patents, and obtained 6 authorizations.

Resume:

2008.09-2011.03 Department of chemical engineering, Tsinghua University, postdoctoral

2011.03-2017.09 assistant researcher, South China Sea Institute of Oceanography, Chinese Academy of Sciences

September 2017 ~ now, associate researcher, ocean college, South China Agricultural University

Educational experience

2004.09-2008.07 Ph.D. in marine biology, Sun Yat sen University

2000.09-2004.07 Hunan Normal University biological science major, Bachelor of Science Degree

research field 

Aquatic microbiology, aquatic animal disease prevention and control, microbial fermentation engineering and biological products

Scientific research projects undertaken:

Host project:

1. NSFC Youth Fund: Study on the mechanism of vp088 in the process of virus infection of grouper iridovirus SGIV (3150207), 2016.01-2018.12

2. General program of Guangdong Provincial Natural Science Foundation: functional study on vp019 of grouper iridovirus SGIV envelope protein (2017a03033180) June 2017-may 2020

3. General program of Guangdong Natural Science Foundation: molecular mechanism of gene expression and regulation of DHA operon of Klebsiella Oceanographica (2015a030313854), August 2015-august 2018

4. Guangdong targeted poverty alleviation science and technology special commissioner project, grouper healthy breeding technology demonstration and promotion (2018a0118), June 2018-june 2020

5. Guangzhou agricultural science and technology special commissioner project, demonstration and promotion of healthy culture technology of perch in California June 2019 to June 2021

6. Innovation and entrepreneurship project of South China Agricultural University, marine fish intestinal probiotics disease resistant function fermentation feed, July 2019-july 2021

7. China Postdoctoral Fund: using red recombination system to knock out LDH and 2,3-butanediol dehydrogenase gene of Klebsiella pneumoniae (20100470365), 2010.01-2011.06

Participating projects:

8. General program of NSFC: molecular mechanism of natural immunity of fleeing host of grouper iridovirus SGIV vp131 (31972837), 2020.01-2023.12

9. Marine fish system virus disease prevention and control post scientist project 2018.05-2020.05

10. 2018 provincial special fund for economic development (for marine economic development) project 2012.01-2015.12

11. National Marine public welfare industry research project: pilot scale technology and product demonstration of 1,3-propanediol production by marine microbial fermentation (201205020-4), 2012.01-2015.12

12. Special subject for regional demonstration of marine economic innovation and development in Guangdong Province: Construction of marine microorganism specific functional enzyme and Biochemical Technology Laboratory (gd2012-d01-002), June 2013 to June 2016

13. Key project of NSFC: Study on the infection mechanism of grouper iridovirus SGIV to host cells at the level of single virus particles (31330082), 2014-2018

14. General program of National Natural Science Foundation of China: mechanism of lysosomal pathway in apoptosis induced by grouper iridovirus SGIV (31472309), 2015.01-2018.12

15. General program of National Natural Science Foundation of China: molecular mechanism of regulation of virus-induced interferon I expression by grouper PIAS1 (31572643), 2016.01-2019.12

16. Guangdong marine fishery science and technology and industry development project: Key Technology for research and development and large-scale preparation of grouper iridovirus vaccine (a201501c01), 2015.06-2018.05

17. Science and technology program of Guangdong Province: Research on prevention and control technology of aquatic economic animal virus (2011a020102002), 2013.01-2015.12,

18. Research and development of immune and disease resistant gene products of grouper (2014j4100213)

Published papers:

1. Sheng Zhou, Deli Song, Xiaofeng Zhou, Xinliang Mao, Xuefeng Zhou, Sunli Wang, Jingguang Wei, Youhua Huang, Wenxiong Wang, Su-Mei Xiao*,  Qiwei Qin*. Characterization of Bacillus subtilis from gastrointestinal tract of hybrid Hulong grouper (Epinephelus fuscoguttatus × E. lanceolatus) and its effects as probiotic additives. Fish and Shellfish Immunology ( IF 3.185 ) 84 (2019) 1115–1124

2. Sheng Zhou*,Youhua Huang, Xinliang Mao, Lili Li, Chuanyu Guo, Yongli Gao and Qiwei Qin* Impact of acetolactate synthase inactivation on 1,3-propanediol fermentation by Klebsiella pneumoniae. Plos ONE. ( IF 2.766 ) 2019 Apr 24;14(4):e0200978.

3. Jingguang Wei, Chen Li, Xin Zhang, Sheng Zhou, Shaoqing Zang, Shina Wei, Qiwei Qin Molecular cloning and characterization of Aos1 and Uba2 from the orange-spotted grouper (Epinephelus coioides) . Fish & Shellfish Immunology ( IF 3.185 )2018;81:343-353.

4. Wang Zhuxi, Zhou Sheng *, Huang Youhua, Wang Shaowen, Huang Xiaohong, Zhou Yongcan, Qin Qiwei *. Actin, a cytoskeleton protein, is involved in the release of iridovirus SGIV. Journal of fisheries, Vol. 41, No. 8, 2017, 1319-1327 (* corresponding author) Wang Zhuxi, Zhou Sheng *, Huang Youhua, Wang Shaowen, Huang Xiaohong, Zhou Yongcan, Qin Qiwei *. Actin filling involved in the release of SGIV from host cells. Job

Books

Hongjuan Liu*, Xianjin OU, Sheng Zhou, Dehua Liu*. Microbial 1,3-Propanediol, Its Copolymerization with Terephthalate, and Applications. P405-426. In: Guo-qiang Chen. Plastics from Bacteria-Natural Functions and Applications. Springer, 2010, 0- 462