郝双丽
姓名:郝双丽
职务:---
职称:首聘副教授
联系方式:haosl@scau.edu.cn
个人简介
郝双丽,1990年7月生,安徽安庆人,博士,首聘副教授。博士毕业于浙江大学生命科学学院,主要从事中华绒螯蟹等甲壳动物生殖生物学研究,已在Cell Death & Disease, Cell and Tissue Research, Aging-US, Gene等期刊上发表SCI文章文章23篇,其中一作/共一/通讯15篇,主持国家自然科学基金青年科学基金1项,作为核心骨干参与国家自然科学基金面上项目、浙江省自然科学基金等3项。
工作经历
2022年12月—至今 bat365官网登录入口 首聘副教授
2020年11月—2022年10月 浙江大学生命科学学院 博士后
研究领域
甲壳动物生殖生物学
主持与参与的科研项目
国家自然科学基金–青年科学基金项目,《自噬作用在中华绒螯蟹精子发生中的功能及KIF1A和KIF5B调控自噬过程的动力学机制》,2022.01-2024.12,项目号:32102786,主持;
国家自然科学基金–面上项目,《Myosin Va 和KIF3A通过介导mTOR和MAPK信号通路调控中华绒螯蟹血淋巴-精巢屏障结构的形成》,2021.01-2024.12,项目号:32072954,参与;
浙江省自然科学基金,《纳米TiO2穿越血睾屏障的相关机制研究》,2020.01-2022.12,项目号:LGF20C120001,参与;
浙江省自然科学基金,《黄喉拟水龟胚胎发育对温度变化的响应及其生理机制》,2016.01-2018.12,项目号:Y16C030013,参与。
论文发表(#为共同一作,*为通讯作者)
Chen KQ, Wei BH, Hao SL*, Yang WX*. A review The PI3K/AKT signaling pathway: How does it regulate development of Sertoli cells and spermatogenic cells? Histology and Histopathology. 2022,7:18457.
Jia K, Wang LM, Hao SL*, Yang WX*. Es-SOX8 regulates the morphological changes of the sperm nucleus of Eriocheir sinensis by activating Es-BMP2 transcription. BIOCELL. 2022, 46(11):2399-2413.
Li ZF, Hao SL*, Wang LM, Qi HY, Wang JM, Tan FQ, Yang WX*. mTORC1/C2 regulate spermatogenesis in Eriocheir sinensis via alterations in the actin filament network and cell junctions. Cell and Tissue Research. 2022, 390(2):293-313.
Hao SL, Ni FD,Wei BH, Li ZF, Yang T, Yang WX*. Es-ATG7 is required for spermatogenesis of Eriocheir sinensis and modulates p53-dependent apoptosis in germ cell. BIOCELL. 2021, 45(4): 971-984.
Ni DQ#, Ma DD#, Hao SL#, Yang WX*, Kovacs T, Tan FQ. Titanium dioxide nanoparticles perturb the blood-testis barrier via disruption of actin-based cell adhesive function. Aging-US. 2021, 13(23): 25440-25452.
Jia L#, Hao SL#, Yang WX*. Nanoparticles induce autophagy via mTOR pathway inhibition and reactive oxygen species generation. Nanomedicine. 2020, 15(19).
Ni FD#, Hao SL#, Yang WX*. Molecular insights into hormone regulation via signaling pathways in Sertoli cells: With discussion on infertility and testicular tumor. Gene. 2020, 753:144812.
Hao SL, Zhang LY, Ping J, Wu XW, Hu JR, Zhang YP*. Molecular cloning and putative functions of KIFC1 for acrosome formation and nuclear reshaping during spermiogenesis in Schlegel’s Japanese Gecko Gekko japonicus. Asian Herpetological Research. 2019, 10(3): 170–182.
Hao SL, Yang WX*. KIFC1 is essential for normal spermatogenesis and its depletion results in early germ cell apoptosis in the Kuruma shrimp, Penaeus (Marsupenaeus) japonicus. Aging-US. 2019, 11(24):12773–12792.
Ni FD#, Hao SL#, Yang WX*. Multiple signaling pathways in Sertoli cells: recent findings in spermatogenesis. Cell Death & Disease. 2019, 10(8):541.
Hao SL, Ni FD, Yang WX*. The dynamics and regulation of chromatin remodeling during spermiogenesis. Gene. 2019, 706:201–210.
Hao SL, Zhang YP*. Ultrastructure of the spermatozoon of the Chinese water snake, Myrrophis (Enhydris) chinensis (Reptilia: Homalopsidae), European Zoological Journal. 2018, 85:1, 350–362.
Hao SL, Ping J, Zhang YP*. Complete mitochondrial genome of Gekko chinensis (Squamata, Gekkonidae). Mitochondrial DNA Part A. 2016, 27(6):4226–4227.
Hao SL, Yu DN, Ping J, Zhou HB, Zhang YP*. Complete mitochondrial genomes of two gecko species, Gekko hokouensis and Gekko japonicus (Squamata, Gekkonidae). Mitochondrial DNA Part B-Resources. 2016, 1(1):346–347.
Hao SL, Pan LL, Fang ZX, Zhang YP*. Comparative studies on sperm ultrastructure of three gecko species, Gekko japonicus, Gekko chinensis and Hemidactylus bowrigii (Reptilia, Squamata, Gekkonidae). Asian Herpetological Research. 2015, 6(3): 189–198.